BDBM602084 US11643417, Ex. No. 110::US11643417, Ex. No. 99

SMILES OC1(CC1)C1CCC(CCN2CCNC(=O)c3oc4ccc(cc4c23)C(F)(F)F)CC1

InChI Key InChIKey=XTQQIPQSBVXLSR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 602084   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM602084(US11643417, Ex. No. 110 | US11643417, Ex. No. 99)
Affinity DataKi:  0.0760nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM602084(US11643417, Ex. No. 110 | US11643417, Ex. No. 99)
Affinity DataKi:  0.133nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent