BDBM602629 2-[1-[2-(4,4-Dimethyl-1-piperidyl)-6- isoxazol-4-yl-6-methyl-4-oxo- chromen-8-yl]ethylamino]benzoic acid, Isomer 1::US11649227, Example 53::US11649227, Example 54::US20230286960, Example 54

SMILES CC(Nc1ccccc1C(O)=O)c1cc(C)cc2c1oc(N1CCC(C)(C)CC1)c(-c1cnoc1)c2=O

InChI Key InChIKey=QMRGSVKOVQUVSI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 602629   

LigandPNGBDBM602629(2-[1-[2-(4,4-Dimethyl-1-piperidyl)-6- isoxazol-4-y...)
Affinity DataIC50:  750nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602629(2-[1-[2-(4,4-Dimethyl-1-piperidyl)-6- isoxazol-4-y...)
Affinity DataIC50: <500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602629(2-[1-[2-(4,4-Dimethyl-1-piperidyl)-6- isoxazol-4-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602629(2-[1-[2-(4,4-Dimethyl-1-piperidyl)-6- isoxazol-4-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602629(2-[1-[2-(4,4-Dimethyl-1-piperidyl)-6- isoxazol-4-y...)
Affinity DataIC50:  750nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602629(2-[1-[2-(4,4-Dimethyl-1-piperidyl)-6- isoxazol-4-y...)
Affinity DataIC50: <500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602629(2-[1-[2-(4,4-Dimethyl-1-piperidyl)-6- isoxazol-4-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM602629(2-[1-[2-(4,4-Dimethyl-1-piperidyl)-6- isoxazol-4-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent