BDBM604954 US11667638, Example 160

SMILES Brc1c(I)cc2[C@@H]3CNCC(C3)Cn2c1=O

InChI Key InChIKey=OCEAINWYIRTVGD-MLWJPKLSSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 604954   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University of Bristol

US Patent
LigandPNGBDBM604954(US11667638, Example 160)
Affinity DataKi:  0.238nMAssay Description:The binding of a group of compounds mentioned above were tested for their affinity at different nAChR subtypes, specifically the α4β2, the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University of Bristol

US Patent
LigandPNGBDBM604954(US11667638, Example 160)
Affinity DataKi:  11.9nMAssay Description:The binding of a group of compounds mentioned above were tested for their affinity at different nAChR subtypes, specifically the α4β2, the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of Bristol

US Patent
LigandPNGBDBM604954(US11667638, Example 160)
Affinity DataKi:  26nMAssay Description:The binding of a group of compounds mentioned above were tested for their affinity at different nAChR subtypes, specifically the α4β2, the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent