BDBM606328 US11685729, Example 49::{3-[1-(2-Fluoro-6-methyl-phenyl)-piperidin-4-yl]-2-oxo-3,4-dihydro-2H-quinazolin-1-yl}-(2-methoxy-phenyl)-aceticacid methyl ester

SMILES COC(=O)C(N1C(=O)N(Cc2ccccc12)C1CCN(CC1)c1c(C)cccc1F)c1ccccc1OC

InChI Key InChIKey=BHCZUSAAWMZHCB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 606328   

TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM606328(US11685729, Example 49 | {3-[1-(2-Fluoro-6-methyl-...)
Affinity DataIC50:  102nMAssay Description:Adherent cells (CHO-K1 C5AR1 beta-arrestin cell line, DiscoverX, CA USA) are washed with PBS, detached by incubation with Dissociation Buffer (Gibco ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent