BDBM609591 US11702418, Example 12-67

SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCN(C)CC1)c1cccc(c1F)C(F)(F)F

InChI Key InChIKey=KOTFONVJHMTHJY-CYBMUJFWSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609591   

TargetSon of sevenless homolog 1 [564-1049]()
Mirati Therapeutics

US Patent
LigandPNGBDBM609591(US11702418, Example 12-67)
Affinity DataKi:  0.360nMAssay Description:Table 22: This Example illustrates that exemplary compounds of the present invention bind to SOS1 and prevent a labeled tracer ligand from occupying ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent