BDBM610462 N-(4-Morpholinopyridin-3-yl)-2-phenylimidazo[1,2-b]pyridazine-8-carboxamide::US10774086, Example 13
SMILES O=C(Nc1cnccc1N1CCOCC1)c1ccnn2cc(nc12)-c1ccccc1
InChI Key InChIKey=KZAWBYUYDLDFQY-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 610462
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of tau 4R1N phosphorylation (unknown origin) at S396 residue transfected in human U2OS cells coexpressing GFP-tagged beta catenin incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair