BDBM614884 A7-43 rac-2-((3R,4R)-4-(((6- (cyclopropyl(4- (difluoromethoxy)benzyl)amino)- 5-fluoropyrimidin-4- yl)amino)methyl)-3- hydroxypiperidin-1-yl)acetamide::US20230271937, Example A7-43

SMILES NC(=O)CN1CC[C@@H](CNc2ncnc(N(Cc3ccc(OC(F)F)cc3)C3CC3)c2F)[C@H](O)C1

InChI Key InChIKey=YZNQMRRFXQEZEZ-MAUKXSAKSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614884   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Nuevolution

US Patent
LigandPNGBDBM614884(A7-43 rac-2-((3R,4R)-4-(((6- (cyclopropyl(4- (difl...)
Affinity DataEC50:  11nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent