BDBM622271 (R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-7-methylquinoline-4-carboxamide::US20230312550, Reference Compound B::US20230406840, Example B

SMILES Cc1ccc2c(ccnc2c1)C(=O)NCC(=O)N1CSC[C@H]1C#N

InChI Key InChIKey=HXNVBHBOYQBEHL-GFCCVEGCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 622271   

TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622271((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-7-m...)
Affinity DataIC50:  5.20nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM622271((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-7-m...)
Affinity DataIC50:  5.20nMAssay Description:Table 3: Compounds were tested in a biochemical inhibition assay using Prolyl endopeptidase, Prolyl Oligopeptidase (hPREP) enzyme at 0.6 nM FAC (R&D ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent