BDBM634327 4-(pyrrolidin-1-yl)-8,14-dioxa-10,19,20-::US20230357269, Example 12

SMILES O=C1NCCCOc2ccc3[nH]nc(-c4cc(CO1)cc(c4)N1CCCC1)c3c2

InChI Key InChIKey=JKPYBZJDEKQKJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634327   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM634327(4-(pyrrolidin-1-yl)-8,14-dioxa-10,19,20- | US20230...)
Affinity DataIC50: <10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent