BDBM634359 4-[(4-methylpiperazin-1-yl)methyl]-8,14-dioxa-::US20230357269, Example 44

SMILES CN1CCN(Cc2cc3COC(=O)NCCCOc4ccc5[nH]nc(-c(c2)c3)c5c4)CC1

InChI Key InChIKey=CBCAIHBHVULUIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634359   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM634359(4-[(4-methylpiperazin-1-yl)methyl]-8,14-dioxa- | U...)
Affinity DataIC50: <10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent