BDBM635362 (S)-N-(5-(2,3-dimethyl-7-morpholino-2H- indazol-5-yl)-2-fluoro-4-methylphenyl)-3-(2,2,2- trifluoroethyl)pyrrolidine-1-carboxamide::US11814384, Example 16

SMILES Cc1n(C)nc2c(cc(cc12)-c1cc(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)c(F)cc1C)N1CCOCC1

InChI Key InChIKey=MZZJLUVPBBYJDT-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635362   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635362((S)-N-(5-(2,3-dimethyl-7-morpholino-2H- indazol-5-...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent