BDBM635363 (S)-N-(2-fluoro-4-methyl-5-(8- morpholinoimidazo[1,2-a]pyridin-6-yl)phenyl)-3- (2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide::US11814384, Example 17

SMILES Cc1cc(F)c(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)cc1-c1cc(N2CCOCC2)c2nccn2c1

InChI Key InChIKey=MTAWOESVPXBSDV-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635363   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635363((S)-N-(2-fluoro-4-methyl-5-(8- morpholinoimidazo[1...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent