BDBM635367 N-(3-(8-hydroxy-4-morpholino-6,7,8,9- tetrahydrobenzo[4,5]imidazo[1,2-a]pyridin-2-yl)- 4-methylphenyl)-2- (trifluoromethyl)isonicotinamide::US11814384, Example 34::US11814384, Example 35

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1cc(N2CCOCC2)c2nc3CCC(O)Cc3n2c1

InChI Key InChIKey=NXYLPZZMBXMMBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 635367   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635367(N-(3-(8-hydroxy-4-morpholino-6,7,8,9- tetrahydrobe...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635367(N-(3-(8-hydroxy-4-morpholino-6,7,8,9- tetrahydrobe...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent