BDBM635440 1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (8-morpholinoimidazo[1,2-b]pyridazin-6- yl)phenyl)-1H-pyrazole-4-carboxamide::US11814384, Example 239::US11814384, Example 242

SMILES Cc1cc(F)c(NC(=O)c2cnn(c2F)C(C)(C)C)cc1-c1cc(N2CCOCC2)c2nccn2n1

InChI Key InChIKey=MHOJJXFQVSMMND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 635440   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635440(1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (8...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635440(1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (8...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent