BDBM635446 1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (2-methyl-8-morpholinoimidazo[1,2-b]pyridazin- 6-yl)phenyl)-1H-pyrazole-4-carboxamide::US11814384, Example 265

SMILES Cc1cn2nc(cc(N3CCOCC3)c2n1)-c1cc(NC(=O)c2cnn(c2F)C(C)(C)C)c(F)cc1C

InChI Key InChIKey=OUGNXTXRQCPXEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635446   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635446(1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (2...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent