BDBM635447 N-(1-(tert-butyl)-5-fluoro-1H-pyrazol-4-yl)-2- fluoro-4-methyl-5-(2-methyl-8- morpholinoimidazo[1,2-a]pyridin-6-yl)benzamide::US11814384, Example 267

SMILES Cc1cn2cc(cc(N3CCOCC3)c2n1)-c1cc(C(=O)Nc2cnn(c2F)C(C)(C)C)c(F)cc1C

InChI Key InChIKey=QBGREABRXKNDCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635447   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635447(N-(1-(tert-butyl)-5-fluoro-1H-pyrazol-4-yl)-2- flu...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent