BDBM635458 2-Tert-butyl-N-{2-fluoro-4-methyl-5-[2-methyl- 8-(morpholin-4-yl)-[1,2,4]triazolo[1,5-a]pyridin- 6-yl]phenyl}-1,2,3-triazole-4-carboxamide::US11814384, Example 303

SMILES Cc1nc2c(cc(cn2n1)-c1cc(NC(=O)c2cnn(n2)C(C)(C)C)c(F)cc1C)N1CCOCC1

InChI Key InChIKey=MDLURUXSKAJTOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635458   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635458(2-Tert-butyl-N-{2-fluoro-4-methyl-5-[2-methyl- 8-(...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent