BDBM635465 2-Fluoro-N-[3-fluoro-1-(1-methylcyclopropyl)pyrazol-4-yl]-4-methyl-5-[2-methyl-8-(morpholin-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]benzamide::US11814384, Example 310

SMILES Cc1nc2c(cc(cn2n1)-c1cc(C(=O)Nc2cn(nc2F)C2(C)CC2)c(F)cc1C)N1CCOCC1

InChI Key InChIKey=IEBQKOSDGRXSSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635465   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM635465(2-Fluoro-N-[3-fluoro-1-(1-methylcyclopropyl)pyrazo...)
Affinity DataIC50:  5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent