BDBM645501 US20240018122, Example 187::methyl 3-[6-(5-chloro-2- fluorophenyl)-4-({2-[3-(4- methylpiperazin-1- yl)propanamido]pyridin-4- yl}amino)pyridazin-3- yl]propanoate

SMILES COC(=O)CCc1nnc(cc1Nc1ccnc(NC(=O)CCN2CCN(C)CC2)c1)-c1cc(Cl)ccc1F

InChI Key InChIKey=GAFMETXHIKMQCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645501   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645501(US20240018122, Example 187 | methyl 3-[6-(5-chloro...)
Affinity DataIC50: <1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent