BDBM647614 (R)-N,N-dimethyl-4-(3-methylmorpholino)-6-(1H-pyrazol-3-yl)pyrazolo[3,4-b]pyrrolo[2,3-d]pyridine-1(6H)-sulfonamide trifluoroacetate ::US20240025899, Compound 3

SMILES C[C@@H]1COCCN1c1nc2n(ncc2c2n(ccc12)S(=O)(=O)N(C)C)-c1cc[nH]n1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647614   

TargetSerine/threonine-protein kinase ATR [14-953](Homo sapiens (Human))
Shanghai De Novo Pharmatech Co.

US Patent
LigandPNGBDBM647614((R)-N,N-dimethyl-4-(3-methylmorpholino)-6-(1H-pyra...)
Affinity DataIC50:  0.510nMAssay Description:In this experiment, the phosphorylation level of substrate protein P53 (Eurofins, 14-952) was detected by HTRF technology to measure the activity of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent