BDBM651793 2-(5-(6-chloro-5-methoxy-3- (1H-pyrazol-4-yl)-1H- pyrrolo[3,2-b]pyridin-2-yl)- 4H-1,2,4-triazol-3-yl)-2,2- difluoroethan-1-ol::US20240051954, Example 5

SMILES COc1nc2c(-c3cn[nH]c3)c([nH]c2cc1Cl)-c1nnc([nH]1)C(F)(F)CO

InChI Key InChIKey=PNMIYCICTONDSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651793   

TargetCyclic GMP-AMP synthase [147-522](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM651793(2-(5-(6-chloro-5-methoxy-3- (1H-pyrazol-4-yl)-1H- ...)
Affinity DataIC50:  97nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent