BDBM67 DMPC Cyclic Urea 47::N-{5-[(4R,5S,6S,7R)-4,7-dibenzyl-3-{5-[(3-fluorophenyl)formamido]pentyl}-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]pentyl}-3-fluorobenzamide

SMILES O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(CCCCCNC(=O)c2cccc(F)c2)C(=O)N(CCCCCNC(=O)c2cccc(F)c2)[C@@H]1Cc1ccccc1

InChI Key InChIKey=SXZREBMMGUVYHI-WESAGZJESA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 67   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM67(DMPC Cyclic Urea 47 | N-{5-[(4R,5S,6S,7R)-4,7-dibe...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM67(DMPC Cyclic Urea 47 | N-{5-[(4R,5S,6S,7R)-4,7-dibe...)
Affinity DataKi:  14nM ΔG°:  -11.1kcal/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed