BDBM81693 4-Substituted Pyrrolidine Ring, 16::4-Substituted Pyrrolidine Ring, 17

SMILES CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)[C@H]2CC(F)CN2C(=O)Nc2ccc(Cl)cc2)c(F)c1

InChI Key InChIKey=NXKSHXRRVMZPFR-IVAFLUGOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 81693   

TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

LigandPNGBDBM81693(4-Substituted Pyrrolidine Ring, 16 | 4-Substituted...)
Affinity DataIC50:  1.20nMAssay Description:FXa inhibition were determined by using an inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

LigandPNGBDBM81693(4-Substituted Pyrrolidine Ring, 16 | 4-Substituted...)
Affinity DataIC50:  7nMAssay Description:FXa inhibition were determined by using an inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed