BDBM82411 CAS_75921-69-6::NDP-MSH

SMILES CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O

InChI Key InChIKey=UAHFGYDRQSXQEB-LEBBXHLNSA-N

Data  7 KI  13 IC50  26 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 82411   

TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.0170nMAssay Description:Evaluated for agonist activity at cloned mammalian Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.132nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataIC50:  3.60nMAssay Description:Inhibitory activity against human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.0230nMAssay Description:Evaluated for agonist activity at cloned mammalian human MSH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory activity against Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.00500nMAssay Description:Decrease in frog skin reflectivity (melanotropic activity).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human melanocortin 5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  1nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.0200nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.800nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed