BDBM86630 JNK-IN-5

SMILES C=CC(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)-c2cccnc2)cc1

InChI Key InChIKey=LUFRTLQRKNBFAZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86630   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM86630(JNK-IN-5)
Affinity DataIC50:  2.11nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM86630(JNK-IN-5)
Affinity DataIC50:  0.960nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM86630(JNK-IN-5)
Affinity DataIC50:  1.93nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed