BDBM8809 5-(4-Aminophenyl)-6-methylthieno[2,3-d]pyrimidin-4-amine::CHEMBL370006::Thienopyrimidine deriv. 6

SMILES Cc1sc2ncnc(N)c2c1-c1ccc(N)cc1

InChI Key InChIKey=XEYSOBWTYDZKAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8809   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8809(5-(4-Aminophenyl)-6-methylthieno[2,3-d]pyrimidin-4...)
Affinity DataIC50:  4.60E+3nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8809(5-(4-Aminophenyl)-6-methylthieno[2,3-d]pyrimidin-4...)
Affinity DataIC50:  4.57E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8809(5-(4-Aminophenyl)-6-methylthieno[2,3-d]pyrimidin-4...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed