BDBM8820 3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-3-methyl-1-(3-methylphenyl)urea::CHEMBL196020::N-[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N-methyl-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 72

SMILES CN(C(=O)Nc1cccc(C)c1)c1ccc(cc1)-c1c(C)sc2ncnc(N)c12

InChI Key InChIKey=ZWLGJBWBMJLKSB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8820   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8820(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  55nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8820(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  55.0nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8820(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  55nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed