BDBM8862 3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-fluorophenyl)-1-(3-methylphenyl)urea::CHEMBL425749::N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-3-fluoro-phenyl]N -(3-methylphenyl)urea::Thienopyrimidine deriv. 88

SMILES Cc1cccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)c(F)c2)c1

InChI Key InChIKey=GWOSGFTZTVFDGQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8862   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8862(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-fluoro...)
Affinity DataIC50:  11nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8862(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-fluoro...)
Affinity DataIC50:  27nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8862(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-fluoro...)
Affinity DataIC50:  10nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8862(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-fluoro...)
Affinity DataIC50:  11.0nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8862(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-fluoro...)
Affinity DataIC50:  11nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8862(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-fluoro...)
Affinity DataIC50:  26.9nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8862(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-fluoro...)
Affinity DataIC50:  27nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed