BDBM8865 3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-fluorophenyl)-1-(3-methylphenyl)urea::CHEMBL371510::N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 91

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2F)-c2csc3ncnc(N)c23)c1

InChI Key InChIKey=GSFKQDWVMKDKSA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8865   

TargetAromatase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8865(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-fluoro...)
Affinity DataIC50:  67nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8865(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-fluoro...)
Affinity DataIC50:  19nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8865(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-fluoro...)
Affinity DataIC50:  38nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8865(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-fluoro...)
Affinity DataIC50:  19.1nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8865(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-fluoro...)
Affinity DataIC50:  19nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8865(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-fluoro...)
Affinity DataIC50:  38.0nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8865(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-2-fluoro...)
Affinity DataIC50:  38nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed