BDBM8903 (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one::CHEMBL103::progesterone
SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
InChI Key InChIKey=RJKFOVLPORLFTN-LEKSSAKUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 8903
Affinity DataKi: 3.5nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Displacement of DHT from human androgen receptor expressed in baculovirus SF-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30.5nMAssay Description:Displacement of dexamethasone from human glucocorticoid receptor expressed in baculovirus SF-12 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human glucocorticoid receptor at 10e-12 to 10e-5 MMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonistic activity against human progesterone receptor in T47D breast cancer cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90nMAssay Description:Agonistic activity against human progesterone receptor in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against human Mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inihibition of human androgen receptor at 10e-12 to 10e-5 MMore data for this Ligand-Target Pair