BDBM92482 CDE-008::US9120744, CDE-008

SMILES Oc1cc(cc(O)c1O)C(=O)OCCOC(=O)c1cc(O)c(O)c(O)c1

InChI Key InChIKey=PFTHQRBULKATPZ-UHFFFAOYSA-N

Data  4 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 92482   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Michigan

LigandPNGBDBM92482(CDE-008 | US9120744, CDE-008)
Affinity DataIC50:  44nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
University of Michigan

LigandPNGBDBM92482(CDE-008 | US9120744, CDE-008)
Affinity DataIC50:  162nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM92482(CDE-008 | US9120744, CDE-008)
Affinity DataKd:  23nMpH: 5.0 T: 2°CAssay Description:To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM92482(CDE-008 | US9120744, CDE-008)
Affinity DataKd:  23nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM92482(CDE-008 | US9120744, CDE-008)
Affinity DataIC50:  370nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University of Michigan

LigandPNGBDBM92482(CDE-008 | US9120744, CDE-008)
Affinity DataIC50: >1.00E+4nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed