BDBM92515 RDR 03785, 11

SMILES Oc1cc2OCOc2cc1C(N1CCOCC1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=AWQPMEGCCWPTRI-UHFFFAOYSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 92515   

TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataKi:  52nMAssay Description:Covalent inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using 4-hydroxyphenyl pyruvic acid as substrate asses...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataKi:  570nMAssay Description:Inhibition of recombinant human MIF tautomerization expressed in Escherichia coli BL21/DE3 using HPP as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataIC50:  360nMAssay Description:Covalent inhibition of MIF (unknown origin) tautomerase activity using 4-hydroxyphenyl pyruvic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataIC50:  570nMAssay Description:Covalent inhibition of human MIF tautomerase activity expressed in Escherichia coli BL21 (DE3) using 4-hydroxyphenyl pyruvic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human MIF tautomerization expressed in Escherichia coli BL21/DE3 using dopa as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataIC50:  6.12E+3nMAssay Description:Inhibition of recombinant human full length MIF expressed in Escherichia coli BL21(DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed