BDBM98595 (2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxo-ethyl]-3-hydroxy-2-(p-tolylmethylsulfonylamino)propanamide::US8476306, 6.21

SMILES Cc1ccc(CS(=O)(=O)N[C@H](CO)C(=O)NCC(=O)NCc2ccc(cc2)C(N)=N)cc1

InChI Key InChIKey=CYBWAZVYPDOAOW-GOSISDBHSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98595   

TargetUrokinase plasminogen activator surface receptor(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98595((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  58nM ΔG°:  -9.83kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98595((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  210nM ΔG°:  -9.07kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98595((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  8.00E+3nM ΔG°:  -6.93kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98595((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  1.80E+4nM ΔG°:  -6.45kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In DepthDetails US Patent