BDBM99917 4-tert-butyl-N-(4-(5-(dimethylamino)pentanamido)phenylcarbamothioyl)benzamide::US8501991, Tenovin 6
SMILES CN(C)CCCCC(=O)Nc1ccc(NC(=S)NC(=O)c2ccc(cc2)C(C)(C)C)cc1
InChI Key InChIKey=BVJSXSQRIUSRCO-UHFFFAOYSA-O
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 99917
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of recombinant human GST or His6-tagged SIRT1 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of recombinant human His6-tagged SIRT2 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 12 mins in presence of bet...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of recombinant human His6-tagged SIRT3 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence of bet...More data for this Ligand-Target Pair