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Found 35 with Last Name = 'pannifer' and Initial = 'ad'
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12407(3-chloro-N-[5-({6-methoxy-7-[3-(morpholin-4-yl)pro...)
Affinity DataIC50: <0.100nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12408(3-chloro-4-fluoro-N-[5-({6-methoxy-7-[3-(morpholin...)
Affinity DataIC50:  0.150nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12405(CHEMBL381724 | N-[5-({6-methoxy-7-[3-(morpholin-4-...)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194411((S)-2,3-dichloro-N-(1-(dimethylamino)-1-oxo-3-phen...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194415(2,3-dichloro-N-((1R,2R)-1-hydroxy-2,3-dihydro-1H-i...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194414((S)-2-chloro-N-(1-(dimethylamino)-1-oxo-3-phenylpr...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12413(CHEMBL204318 | N-[5-({6-methoxy-7-[3-(morpholin-4-...)
Affinity DataIC50:  17nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194420((S)-2,3-dibromo-N-(1-(dimethylamino)-1-oxo-3-pheny...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194417((S)-2-bromo-N-(1-(dimethylamino)-1-oxo-3-phenylpro...)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM24363(2-chloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)...)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194410(2,3-dichloro-N-((1R,2R)-6-fluoro-1-hydroxy-2,3-dih...)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50065954((S)-5-chloro-N-(1-(dimethylamino)-1-oxo-3-phenylpr...)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12409(3-bromo-N-[5-({6-methoxy-7-[3-(morpholin-4-yl)prop...)
Affinity DataIC50:  70nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12410(4-ethyl-N-[5-({6-methoxy-7-[3-(morpholin-4-yl)prop...)
Affinity DataIC50:  85nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50136437(5-Chloro-1H-indole-2-carboxylic acid (2-oxo-1,2,3,...)
Affinity DataIC50:  86nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194418(2,3-dichloro-N-((1R,2R)-6-chloro-1-hydroxy-2,3-dih...)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM14210(4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-mo...)
Affinity DataIC50:  110nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM24361(2,3-dichloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3...)
Affinity DataIC50:  132nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194423(2,3-dichloro-N-(2,3-dihydro-1H-inden-2-yl)-4H-thie...)
Affinity DataIC50:  197nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194412(2-CHLORO-N-[(1R,2R)-1-HYDROXY-2,3-DIHYDRO-1H-INDEN...)
Affinity DataIC50:  319nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194424((S)-3-chloro-N-(1-(methylamino)-1-oxo-3-phenylprop...)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12403(CHEMBL382590 | N-{4-[(6,7-dimethoxyquinazolin-4-yl...)
Affinity DataIC50:  393nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194413((S)-2-chloro-N-(1-(methylamino)-1-oxo-3-phenylprop...)
Affinity DataIC50:  577nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12406(CHEMBL206266 | N-[2-({6-methoxy-7-[3-(morpholin-4-...)
Affinity DataIC50:  629nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12412(CHEMBL203507 | N-[5-({6-methoxy-7-[3-(morpholin-4-...)
Affinity DataIC50:  690nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194422(2-chloro-N-(2,3-dihydro-1H-inden-2-yl)-6H-thieno[2...)
Affinity DataIC50:  806nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194421((S)-N-(1-(dimethylamino)-1-oxo-3-phenylpropan-2-yl...)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibitory concentration against Protein tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12411(4-(dipropylsulfamoyl)-N-[5-({6-methoxy-7-[3-(morph...)
Affinity DataIC50:  3.90E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells, was incubated at room temperature with substrate, and test compounds in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194416((S)-2,3-dibromo-N-(1-(dimethylamino)-1-oxo-3-pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194419((S)-2,3-dibromo-N-(1-(dimethylamino)-1-oxo-3-pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50166432(5-Biphenyl-3-yl-1,1-dioxo-1lambda*6*-[1,2,5]thiadi...)
Affinity DataIC50:  1.32E+5nMAssay Description:Inhibitory concentration against Protein tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50166433(5-(2-Methoxy-phenyl)-1,1-dioxo-1lambda*6*-[1,2,5]t...)
Affinity DataIC50:  1.38E+5nMAssay Description:Inhibitory concentration against Protein tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50166431(1,1-Dioxo-5-o-tolyl-1lambda*6*-[1,2,5]thiadiazolid...)
Affinity DataIC50:  2.03E+5nMAssay Description:Inhibitory concentration against Protein tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50166434(1,1-Dioxo-5-phenyl-1lambda*6*-[1,2,5]thiadiazolidi...)
Affinity DataIC50:  1.61E+6nMAssay Description:Inhibitory concentration against Protein tyrosine phosphatase 1BMore data for this Ligand-Target Pair