Affinity DataKi: 5.90nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against hMC1R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Agonist activity at human MC5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Agonist activity at human MC5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Agonist activity at human MC5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair