Affinity DataIC50: 0.316nMpH: 9.0 T: 2°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [3H]anandamide was evaluated by using rat brain homogenate preparations. [3H]Ethanola...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 2 using osteosarcomes cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetThromboxane A2 receptor(Homo sapiens (Human))
FacultéS Universitaires N.D. De La Paix
Curated by ChEMBL
FacultéS Universitaires N.D. De La Paix
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory concentration of compound against thromboxane A2 receptorMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Laboratoires Innothera
Curated by ChEMBL
Laboratoires Innothera
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The compound was evaluated for its inhibitory activity against 5-lipoxygenase using granulocytes-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
TargetThromboxane-A synthase(Homo sapiens (Human))
FacultéS Universitaires N.D. De La Paix
Curated by ChEMBL
FacultéS Universitaires N.D. De La Paix
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory concentration of compound against thromboxane A2 synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 9.0 T: 2°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [3H]anandamide was evaluated by using rat brain homogenate preparations. [3H]Ethanola...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
TargetThromboxane A2 receptor(Homo sapiens (Human))
FacultéS Universitaires N.D. De La Paix
Curated by ChEMBL
FacultéS Universitaires N.D. De La Paix
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory concentration of compound against thromboxane A2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Facult£S Universitaires Notre-Dame De La Paix (Fundp)
Curated by ChEMBL
Facult£S Universitaires Notre-Dame De La Paix (Fundp)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV1 integrase strand transfer activity after 1 hr by gel based assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Facult£S Universitaires Notre-Dame De La Paix (Fundp)
Curated by ChEMBL
Facult£S Universitaires Notre-Dame De La Paix (Fundp)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV1 integrase strand transfer activity after 1 hr by gel based assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 2 using osteosarcomes cellsMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Facult£S Universitaires Notre-Dame De La Paix (Fundp)
Curated by ChEMBL
Facult£S Universitaires Notre-Dame De La Paix (Fundp)
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 integrase strand transfer activity after 1 hr by gel based assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Inhibition of human recombinant FAAH-mediated [3H]AEA hydrolysis after 10 mins by liquid scintillation assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Laboratoires Innothera
Curated by ChEMBL
Laboratoires Innothera
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-lipoxygenase activity of compound evaluated as determined by the inhibition of calcium ionophore-induced leukotriene B4 production in...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 157nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair