Compile Data Set for Download or QSAR
maximum 50k data
Found 468 with Last Name = 'wong' and Initial = 'ch'
TargetHIV-1 protease(Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM586099(BDBM50064200 | TL-3)
Affinity DataKi:  1.5nM ΔG°:  -52.4kJ/molepH: 5.6 T: 2°CAssay Description:Inhibition of HIV-protease activity for selected acids at P3-P3' positions. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataKi:  1.5nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)
Affinity DataKi:  1.70nM IC50:  6nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMedMMDB

TargetHIV-1 protease(Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM586090(P3-P3' Entry 8)
Affinity DataKi:  2nM ΔG°:  -51.6kJ/molepH: 5.6 T: 2°CAssay Description:Inhibition of HIV-protease activity for selected acids at P3-P3' positions. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)
Affinity DataKi:  2.70nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  4nM IC50:  13nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59242(Benzotriazole ester, 8 | acs.jmedchem.1c00409_ST.6...)
Affinity DataKi:  7.5nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataKi:  8nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  9.70nM IC50:  17nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)
Affinity DataKi:  10nM IC50:  19nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMedMMDB

TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072685((3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperid...)
Affinity DataKi:  11nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59240(Benzotriazole ester, 6 | acs.jmedchem.1c00409_ST.8)
Affinity DataKi:  11.1nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59239(Benzotriazole ester, 5 | acs.jmedchem.1c00409_ST.9)
Affinity DataKi:  12.1nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59243(Benzotriazole ester, 9 | acs.jmedchem.1c00409_ST.1...)
Affinity DataKi:  12.3nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  13nM IC50:  24nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59244(Benzotriazole ester, 10 | acs.jmedchem.1c00409_ST....)
Affinity DataKi:  13.8nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59238(Benzotriazole ester, 4 | acs.jmedchem.1c00409_ST.1...)
Affinity DataKi:  17.4nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324676((R)-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosp...)
Affinity DataKi:  18nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cells assessed as inhibition of SEW2871-induced [35S]GTPgamma bindingMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataKi:  18nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Affinity DataKi:  19nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59237(Benzotriazole ester, 3 | acs.jmedchem.1c00409_ST.1...)
Affinity DataKi:  19.5nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)
Affinity DataKi:  22nM IC50:  39nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMedMMDB

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59241(Benzotriazole ester, 7)
Affinity DataKi:  22.9nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit beta(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM40762(Iminocyclitol, 4)
Affinity DataKi:  24nMAssay Description:Hexosaminidase activity assay was measured by fluorometry, VersaFluor Fluorometer from Bio-Rad.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)
Affinity DataKi:  27nM IC50:  46nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMedMMDB

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  30nM IC50:  52nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11234((2S)-N-(2-chloro-4-nitrophenyl)-2-{[4-(dimethylami...)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/mole IC50:  60nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Affinity DataKi:  30nMAssay Description:Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans F1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119876(SL932 | US9073941, 503)
Affinity DataKi:  37nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit beta(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM40761(Iminocyclitol, 3)
Affinity DataKi:  40nMAssay Description:Hexosaminidase activity assay was measured by fluorometry, VersaFluor Fluorometer from Bio-Rad.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046314(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataKi:  46nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50072687((S)-2-Amino-3-hydroxy-N-(3,4,5-trihydroxy-2-hydrox...)
Affinity DataKi:  47nMAssay Description:Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit beta(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM40760(Iminocyclitol, 2)
Affinity DataKi:  65nMAssay Description:Hexosaminidase activity assay was measured by fluorometry, VersaFluor Fluorometer from Bio-Rad.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324676((R)-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosp...)
Affinity DataKi:  77nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cells assessed as inhibition of S1P-induced [35S]GTPgamma bindingMore data for this Ligand-Target Pair
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119876(SL932 | US9073941, 503)
Affinity DataKi:  78nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119877(SL809 | US9073941, 502)
Affinity DataKi:  93nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM40765(Iminocyclitol, 8)
Affinity DataKi:  100nMAssay Description:Hexosaminidase activity assay was measured by fluorometry, VersaFluor Fluorometer from Bio-Rad.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataKi:  100nMAssay Description:Inhibition constant was determined against epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119878(SL827 | US9073941, 500)
Affinity DataKi:  140nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119880(SL418)
Affinity DataKi:  143nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119878(SL827 | US9073941, 500)
Affinity DataKi:  155nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119877(SL809 | US9073941, 502)
Affinity DataKi:  155nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119879(SL917 | US9073941, 505)
Affinity DataKi:  233nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit beta(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM40759(Iminocyclitol, 1)
Affinity DataKi:  240nMAssay Description:Hexosaminidase activity assay was measured by fluorometry, VersaFluor Fluorometer from Bio-Rad.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119879(SL917 | US9073941, 505)
Affinity DataKi:  289nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119880(SL418)
Affinity DataKi:  333nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50366919(CHEMBL610389)
Affinity DataKi:  376nMAssay Description:Compound was tested for binding affinity against Fucosyltransferase 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50366918(CHEMBL610391)
Affinity DataKi:  437nMAssay Description:Compound was tested for binding affinity against Fucosyltransferase 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50366916(CHEMBL610390)
Affinity DataKi:  511nMAssay Description:Compound was tested for binding affinity against Fucosyltransferase 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11261(dipeptidomimetic unsaturated ester 18c | ethyl (2E...)
Affinity DataKi:  520nM ΔG°:  -35.9kJ/mole IC50:  1.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 468 total ) | Next | Last >>
Jump to: