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Found 138 with Last Name = 'pippin' and Initial = 'da'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  7nMAssay Description:Inhibition of VEGFR2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  13nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474381(US10858368, Entry 1 | US11319327, Entry 1)
Affinity DataIC50:  18nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474381(US10858368, Entry 1 | US11319327, Entry 1)
Affinity DataIC50:  18nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  26nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  33nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  33nMAssay Description:Inhibition of Tie2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474387(US10858368, Entry 7 | US11319327, Entry 7)
Affinity DataIC50:  34nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474387(US10858368, Entry 7 | US11319327, Entry 7)
Affinity DataIC50:  34nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  35nMAssay Description:Inhibition of EPHA2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312184(1-(2-hydroxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  37nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  37nMAssay Description:Inhibition of EphB4 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  37nMAssay Description:Inhibition of Tie2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474388(US10858368, Entry 8 | US11319327, Entry 8)
Affinity DataIC50:  46nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474388(US10858368, Entry 8 | US11319327, Entry 8)
Affinity DataIC50:  46nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474394(US10858368, Entry 14 | US11319327, Entry 14)
Affinity DataIC50:  47nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474394(US10858368, Entry 14 | US11319327, Entry 14)
Affinity DataIC50:  47nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  49nMAssay Description:Inhibition of EphB4 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474396(US10858368, Entry 16 | US11319327, Entry 16)
Affinity DataIC50:  56nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474396(US10858368, Entry 16 | US11319327, Entry 16)
Affinity DataIC50:  56nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  62nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474390(US10858368, Entry 10 | US11319327, Entry 10)
Affinity DataIC50:  64nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474390(US10858368, Entry 10 | US11319327, Entry 10)
Affinity DataIC50:  64nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312187(1-(2-chloro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  66nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  67nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474400(US10858368, Entry 20 | US11319327, Entry 20)
Affinity DataIC50:  67nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474400(US10858368, Entry 20 | US11319327, Entry 20)
Affinity DataIC50:  67nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312200(1-(3-(8-(methyl(pyridin-4-ylmethyl)amino)imidazo[1...)
Affinity DataIC50:  69nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  71nMAssay Description:Inhibition of VEGFR3 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  75nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474401(US10858368, Entry 21 | US11319327, Entry 21)
Affinity DataIC50:  75nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474401(US10858368, Entry 21 | US11319327, Entry 21)
Affinity DataIC50:  75nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312178(1-(5-chloro-2-methoxyphenyl)-3-(3-(8-(pyridin-4-yl...)
Affinity DataIC50:  77nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474391(US10858368, Entry 11 | US11319327, Entry 11)
Affinity DataIC50:  77nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474391(US10858368, Entry 11 | US11319327, Entry 11)
Affinity DataIC50:  77nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312175(1-(2-methoxy-5-methylphenyl)-3-(3-(8-(pyridin-4-yl...)
Affinity DataIC50:  78nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474383(US10858368, Entry 3 | US11319327, Entry 3)
Affinity DataIC50:  81nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474383(US10858368, Entry 3 | US11319327, Entry 3)
Affinity DataIC50:  81nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474398(US10858368, Entry 18 | US11319327, Entry 18)
Affinity DataIC50:  86nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474398(US10858368, Entry 18 | US11319327, Entry 18)
Affinity DataIC50:  86nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474386(US10858368, Entry 6 | US11319327, Entry 6)
Affinity DataIC50:  93nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474386(US10858368, Entry 6 | US11319327, Entry 6)
Affinity DataIC50:  93nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474393(US10858368, Entry 13 | US11319327, Entry 13)
Affinity DataIC50:  96nMAssay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM474393(US10858368, Entry 13 | US11319327, Entry 13)
Affinity DataIC50:  96nMAssay Description:A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  100nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  100nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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