TargetTranslocator protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 8.90nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.920nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant RET expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by microbeta liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 20 mins followed by substrate addition measured after 2 mins by El...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 20 mins followed by substrate addition measured after 2 mins by El...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 20 mins followed by substrate addition measured after 2 mins by El...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 20 mins followed by substrate addition measured after 2 mins by El...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant RET expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by ChEMBL
Experimental Therapeutics Centre
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged GSK-3beta expressed in Sf9 insect cells using prephosphorylated polypeptide as subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant GST-Chk1after 30 minsMore data for this Ligand-Target Pair