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Found 20 with Last Name = 'kumarasinghe' and Initial = 'ir'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50346873(CHEMBL1797652)
Affinity DataKi:  4.40nMAssay Description:Inhibition of recombinant LSD1 (178 to 831) (unknown origin) expressed in baculovirus infected insect Sf9 cells using diMeK4H3-21 as substrate by per...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50446141(CHEMBL3108901)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant LSD1 using di-methylated H3-K4 peptide as substrate assessed as release of H2O2 preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM101302(CHEMBL3108900 | US8524717, 57)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant LSD1 using di-methylated H3-K4 peptide as substrate assessed as release of H2O2 preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50458057(CHEMBL4210908)
Affinity DataKi:  40nMAssay Description:Inhibition of LSD1/CoREST (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50346870(CHEMBL1797647)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant human LSD1 expressed in Escherichia coli using methylated H3-K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1 [4-485](Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50346870(CHEMBL1797647)
Affinity DataKi:  50nMAssay Description:Inhibition of recombinant human LSD1/CoREST complex expressed in Escherichia coli using methylated H3-K4 peptide as substrate by peroxidase-coupled a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50346875(CHEMBL1797648)
Affinity DataKi:  107nMAssay Description:Inhibition of recombinant LSD1 (178 to 831) (unknown origin) expressed in baculovirus infected insect Sf9 cells using diMeK4H3-21 as substrate by per...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50446142(CHEMBL3108892)
Affinity DataKi:  120nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) using di-methylated H3-K4 peptide as substrate incubated for 5 mins prior to substrate addition by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50446143(CHEMBL3108897)
Affinity DataKi:  385nMAssay Description:Competitive inhibition of recombinant LSD1 (unknown origin) using H3K4Me2 peptide as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50346869(CHEMBL1797646)
Affinity DataKi:  1.80E+3nMAssay Description:Competitive inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using H3K4 peptide as substrate by Dixon p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50458056(CHEMBL4208031)
Affinity DataIC50:  107nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50458056(CHEMBL4208031)
Affinity DataIC50:  107nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50458055(CHEMBL4214605)
Affinity DataIC50:  136nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50458055(CHEMBL4214605)
Affinity DataIC50:  136nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50446143(CHEMBL3108897)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50446143(CHEMBL3108897)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) using di-methylated H3-K4 peptide as substrate incubated for 5 mins prior to substrate addition by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of MAO-B (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of MAO-A (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50458055(CHEMBL4214605)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-A (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50458055(CHEMBL4214605)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-B (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed