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Found 62 with Last Name = 'morton' and Initial = 'jd'
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of chymotrypsin like activity of 26S proteasome beta 5 subunit (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
TargetCalpain-2 catalytic subunit(Sus scrofa)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503849(CHEMBL4590466)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50114340((S)-2-(4-Fluoro-benzenesulfonylamino)-N-((S)-1-for...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358131(CHEMBL1923954)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358138(CHEMBL1923961)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358137(CHEMBL1923960)
Affinity DataIC50:  14nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358132(CHEMBL1923955)
Affinity DataIC50:  14nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358140(CHEMBL1923963)
Affinity DataIC50:  18nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358134(CHEMBL1923957)
Affinity DataIC50:  23nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25891((2S)-2-[(5-formyl-1H-pyrrol-2-yl)formamido]-3-meth...)
Affinity DataIC50:  25nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Sus scrofa)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503846(CHEMBL4540394)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358133(CHEMBL1923956)
Affinity DataIC50:  27nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358139(CHEMBL1923962)
Affinity DataIC50:  28nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358153(CHEMBL1921830)
Affinity DataIC50:  30nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358136(CHEMBL1923959)
Affinity DataIC50:  31nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Sus scrofa)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503847(CHEMBL4574306)
Affinity DataIC50:  34nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358152(CHEMBL1921829)
Affinity DataIC50:  85nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25890((2S)-2-[(5-formylthiophen-2-yl)formamido]-3-methyl...)
Affinity DataIC50:  85nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25892((2S)-2-[(4-formyl-1H-pyrrol-2-yl)formamido]-3-meth...)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25889((2S)-2-[(5-formylfuran-2-yl)formamido]-3-methyl-N-...)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25887((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25894((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50:  110nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358142(CHEMBL1923965)
Affinity DataIC50:  130nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25886((2S)-2-(furan-2-ylformamido)-3-methyl-N-[(2S)-4-me...)
Affinity DataIC50:  135nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503849(CHEMBL4590466)
Affinity DataIC50:  139nMAssay Description:Inhibition of chymotrypsin like activity of 26S proteasome beta 5 subunit (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25895(N-heterocyclic dipeptide aldehyde, 13 | methyl 5-{...)
Affinity DataIC50:  140nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25893((2S)-2-[(5-formyl-1-methyl-1H-pyrrol-2-yl)formamid...)
Affinity DataIC50:  150nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25893((2S)-2-[(5-formyl-1-methyl-1H-pyrrol-2-yl)formamid...)
Affinity DataIC50:  150nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Sus scrofa)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503845(CHEMBL4531762)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358155(CHEMBL1921832)
Affinity DataIC50:  180nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503847(CHEMBL4574306)
Affinity DataIC50:  189nMAssay Description:Inhibition of chymotrypsin like activity of 26S proteasome beta 5 subunit (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503848(CHEMBL4475662)
Affinity DataIC50:  220nMAssay Description:Inhibition of chymotrypsin like activity of 26S proteasome beta 5 subunit (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358143(CHEMBL1923966)
Affinity DataIC50:  260nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503845(CHEMBL4531762)
Affinity DataIC50:  269nMAssay Description:Inhibition of chymotrypsin like activity of 26S proteasome beta 5 subunit (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358148(CHEMBL1921825)
Affinity DataIC50:  280nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25891((2S)-2-[(5-formyl-1H-pyrrol-2-yl)formamido]-3-meth...)
Affinity DataIC50:  290nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25895(N-heterocyclic dipeptide aldehyde, 13 | methyl 5-{...)
Affinity DataIC50:  290nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358157(CHEMBL1921834)
Affinity DataIC50:  295nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25888((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50:  315nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25894((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50:  340nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25890((2S)-2-[(5-formylthiophen-2-yl)formamido]-3-methyl...)
Affinity DataIC50:  440nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503846(CHEMBL4540394)
Affinity DataIC50:  514nMAssay Description:Inhibition of chymotrypsin like activity of 26S proteasome beta 5 subunit (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25892((2S)-2-[(4-formyl-1H-pyrrol-2-yl)formamido]-3-meth...)
Affinity DataIC50:  530nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358135(CHEMBL1923958)
Affinity DataIC50:  630nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25888((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50:  650nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25887((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50:  680nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358154(CHEMBL1921831)
Affinity DataIC50:  700nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25886((2S)-2-(furan-2-ylformamido)-3-methyl-N-[(2S)-4-me...)
Affinity DataIC50:  790nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358141(CHEMBL1923964)
Affinity DataIC50:  830nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50358150(CHEMBL1921827)
Affinity DataIC50:  850nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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