Affinity DataKi: 0.600nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]SCH23390 from human D1 receptor expressed in Ltk cellMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibitory constant aganist Protease-activated receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Inhibition of human BACE1 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Inhibition of human BACE2 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human BACE2 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibitory constant aganist Protease-activated receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of human BACE1 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human BACE1 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human BACE2 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of [125I]pig PPY from human NPY1 receptor expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Binding affinity towards human muscarinic M1 receptor in CHO-KI cells using [3H]- QNB as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >42nMAssay Description:Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Inhibition of human BACE1 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligandMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]SCH23390 from human D1 receptor expressed in Ltk cellMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I]pig PPY from human NPY1 receptor expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair