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Found 473 with Last Name = 'mccarthy' and Initial = 'o'
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50190543(1-((2R,4S,5R)-4-hydroxy-5-((tritylamino)methyl)-te...)
Affinity DataKi:  200nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50173539(1-(4-Hydroxy-5-trityloxymethyl-tetrahydro-furan-2-...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50190568(1-(6-(tritylamino)hexyl)pyrimidine-2,4(1H,3H)-dion...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266744(1-((2R,4S,5R)-5-((tert-butyldiphenylsilyloxy)methy...)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50190557(1-(5-(tritylamino)pentyl)pyrimidine-2,4(1H,3H)-dio...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266819(1-(6-(tert-butyldiphenylsilylamino)hexyl)pyrimidin...)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50173539(1-(4-Hydroxy-5-trityloxymethyl-tetrahydro-furan-2-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266848(1-[N-(3-triphenylmethylaminopropyl)-acetamide] ura...)
Affinity DataKi:  2.31E+4nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266847(1-[N-(2-triphenylmethylaminoethyl)-acetamide] urac...)
Affinity DataKi:  3.73E+4nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50190543(1-((2R,4S,5R)-4-hydroxy-5-((tritylamino)methyl)-te...)
Affinity DataKi:  4.60E+4nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341705(CHEMBL1766652 | rac-1-[2-(Carboxy)-4-(triphenylmet...)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341704(CHEMBL1766653 | rac-1-[2-(Acetamide)-4-(triphenylm...)
Affinity DataKi:  9.80E+4nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341697(CHEMBL1766641 | rac-1-[2-(Methoxyethylamido)-4-tri...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341700(CHEMBL1766638 | rac-1-[2-(Carboethoxyethylamido)-4...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341708(CHEMBL1766649 | rac-1-[2-(Diethylamido)-4-(tert-bu...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341699(CHEMBL1766639 | rac-1-[2-(N,N-Dimethylaminoethylam...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341707(CHEMBL1766650 | rac-benzyl 4-(4-(tert-butyldipheny...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341698(CHEMBL1766640 | rac-1-(2-Morpholinamido-4-tritylox...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341706(CHEMBL1766651 | rac-benzyl 2-((2,4-dioxo-3,4-dihyd...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341693(CHEMBL1766645 | rac-1-[2-(Carboxy)-4-(tert-butyldi...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341703(CHEMBL1766635 | rac-1-(2-Amido-4-trityloxybutyl)ur...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341692(CHEMBL1766646 | rac-1-[2-(Acetamide)-4-(tert-butyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341702(CHEMBL1766636 | rac-1-(2-Dimethylamido-4-trityloxy...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341710(CHEMBL1766647 | rac-1-[2-(Methylamido)-4-(tert-but...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341701(CHEMBL1766637 | rac-1-[2-(tert-Butyldiphenylsilylo...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341709(CHEMBL1766648 | rac-1-[2-(Ethylamido)-4-(tert-buty...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341696(CHEMBL1766642 | rac-1-[2-(N-Methylpiperazine)amido...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341695(CHEMBL1766643 | rac-1-[2-(Hydroxyethylamido)-4-tri...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50341694(CHEMBL1766644 | rac-1-[2-(Carboxyethylamido)-4-tri...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human dUTPase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266744(1-((2R,4S,5R)-5-((tert-butyldiphenylsilyloxy)methy...)
Affinity DataKi:  8.06E+5nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266873(1-[N-(triphenylmethylaminoethyl)-N-(aminoethyl) ac...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266820(CHEMBL475993 | N-[3-(tert-butyl diphenyl silanylox...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266874(1-[N-(triphenylmethyl) diaminodi (n-propyl) acetam...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266846(CHEMBL477035 | N-[4-(tert-butyl diphenyl silanylox...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266849(1-[N-(3-triphenylmethylaminobutyl)-acetamide] urac...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266820(CHEMBL475993 | N-[3-(tert-butyl diphenyl silanylox...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266849(1-[N-(3-triphenylmethylaminobutyl)-acetamide] urac...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266873(1-[N-(triphenylmethylaminoethyl)-N-(aminoethyl) ac...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266874(1-[N-(triphenylmethyl) diaminodi (n-propyl) acetam...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266875(1-[N-hydroxyethyl-N-(triphenylmethyl amino) ethyl-...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50190557(1-(5-(tritylamino)pentyl)pyrimidine-2,4(1H,3H)-dio...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266875(1-[N-hydroxyethyl-N-(triphenylmethyl amino) ethyl-...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266847(1-[N-(2-triphenylmethylaminoethyl)-acetamide] urac...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266848(1-[N-(3-triphenylmethylaminopropyl)-acetamide] ura...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266846(CHEMBL477035 | N-[4-(tert-butyl diphenyl silanylox...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50266819(1-(6-(tert-butyldiphenylsilylamino)hexyl)pyrimidin...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
University Of Wales Cardiff

Curated by ChEMBL
LigandPNGBDBM50190568(1-(6-(tritylamino)hexyl)pyrimidine-2,4(1H,3H)-dion...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50191587(CHEMBL3968417)
Affinity DataIC50:  1nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50191486(CHEMBL3959248)
Affinity DataIC50:  1nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataIC50:  2nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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