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Found 120 with Last Name = 'de la fuente' and Initial = 't'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001832(CHEMBL365569)
Affinity DataKi:  0.130nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001827(CHEMBL363792)
Affinity DataKi:  0.130nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001843(CHEMBL373322)
Affinity DataKi:  0.200nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001826(CHEMBL372879)
Affinity DataKi:  0.200nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50403827(CHEMBL414628)
Affinity DataKi:  0.320nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50403827(CHEMBL414628)
Affinity DataKi:  0.320nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055575(CHEMBL3321794)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(MOUSE)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM86428(SB-258585)
Affinity DataKi:  0.75nMAssay Description:Antagonist activity at mouse wild type 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001824(CHEMBL282971)
Affinity DataKi:  0.790nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50130270(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50090527(1-(Naphthalene-1-sulfonyl)-6-(octahydro-indolizin-...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001828(CHEMBL427155)
Affinity DataKi:  0.790nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001829(CHEMBL433946)
Affinity DataKi:  0.790nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM28583(5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...)
Affinity DataKi:  1nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001835(CHEMBL372006 | LY-485731)
Affinity DataKi:  1nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50090530(6-(1,2,3,5,8,8a-Hexahydro-indolizin-7-yl)-1-(napht...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001830(CHEMBL188600)
Affinity DataKi:  1.30nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50163052(6-Chloro-imidazo[2,1-b]thiazole-5-sulfonic acid [1...)
Affinity DataKi:  2nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001825(CHEMBL97158 | SB-331711)
Affinity DataKi:  2nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM86428(SB-258585)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055574(CHEMBL3321798)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50106250(CHEMBL93868 | N,N-dimethyl-2-(1-(phenylsulfonyl)-1...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001821(CHEMBL364039)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50130268(CHEMBL329383 | N-(2,5-Dibromo-3-fluoro-phenyl)-4-m...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataKi:  4nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001840(CHEMBL191385)
Affinity DataKi:  5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50304001(CHEMBL584690 | [4-(4-Methylpiperazin-1-yl)-1H-benz...)
Affinity DataKi:  5nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(MOUSE)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50304001(CHEMBL584690 | [4-(4-Methylpiperazin-1-yl)-1H-benz...)
Affinity DataKi:  5nMAssay Description:Antagonist activity at mouse wild type 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001822(CHEMBL370672)
Affinity DataKi:  6.30nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267832(1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50106248((4S,5S)-4-Dimethylamino-1-(toluene-4-sulfonyl)-1,3...)
Affinity DataKi:  7.90nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM34150(4-(3-methyl-1H-indole-1-sulfonyl)aniline, 8 | CHEM...)
Affinity DataKi:  13nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50304003(1-Naphthyl(4-piperazin-1-yl-1H-benzimidazol-2-yl)m...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50304003(1-Naphthyl(4-piperazin-1-yl-1H-benzimidazol-2-yl)m...)
Affinity DataKi:  15nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50304002(2-(1-Naphthylmethyl)-4-piperazin-1-yl-1H-benzimida...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50303997(2-Benzyl-4-(4-methylpiperazin-1-yl)-1H-benzimidazo...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50090524(4-Amino-N-(2,6-bis-methylamino-pyridin-4-yl)-benze...)
Affinity DataKi:  16nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50304002(2-(1-Naphthylmethyl)-4-piperazin-1-yl-1H-benzimida...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50303999(4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H...)
Affinity DataKi:  17nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50001837(CHEMBL191121)
Affinity DataKi:  20nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055580(CHEMBL3321778)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50106261(CHEMBL316881 | [3-(2-Dimethylamino-ethyl)-5-methox...)
Affinity DataKi:  25nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50304000(4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...)
Affinity DataKi:  27nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055581(CHEMBL3321777)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055578(CHEMBL3321795)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50303998(2-Benzyl-4-piperazin-1-yl-1H-benzimidazole | CHEMB...)
Affinity DataKi:  31nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50203139(4-(1,2,3,4-Tetrahydro-carbazole-9-sulfonyl)-phenyl...)
Affinity DataKi:  32nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50304001(CHEMBL584690 | [4-(4-Methylpiperazin-1-yl)-1H-benz...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055579(CHEMBL3321793)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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