Compile Data Set for Download or QSAR
maximum 50k data
Found 124 with Last Name = 'green' and Initial = 'tp'
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12255(AZD0530 | CHEMBL217092 | Compound 33 | N-(5-chloro...)
Affinity DataIC50:  2.70nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12241(AZD0530 analogue 19 | N-(5-chloro-2H-1,3-benzodiox...)
Affinity DataIC50:  3nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12250(AZD0530 analogue 28 | N-(5-Chloro-1,3-benzodioxol-...)
Affinity DataIC50:  4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12243(AZD0530 analogue 21 | N-(2-chloro-5-methoxyphenyl)...)
Affinity DataIC50: <4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12247(AZD0530 analogue 25 | N-(5-chloro-2H-1,3-benzodiox...)
Affinity DataIC50: <4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12252(AZD0530 analogue 30 | N-(5-Chloro-1,3-benzodioxol-...)
Affinity DataIC50: <4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12237(AZD0530 analogue 15 | N-(5-chloro-2H-1,3-benzodiox...)
Affinity DataIC50: <4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12231(AZD0530 analogue 9 | N-(2-chloro-5-methoxyphenyl)-...)
Affinity DataIC50: <4nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6219(BMCL182776 Compound 1 | Chlorobenzodioxole deriv. ...)
Affinity DataIC50: <4nMT: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6211(Benzodioxole deriv. 20 | N-(5-Bromo-1,3-benzodioxo...)
Affinity DataIC50: <4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6210(Benzodioxole deriv. 19 | N-(5-Chloro-1,3-benzodiox...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6204(Benzofuran deriv. 13 | N-(3-Chloro-1-benzofuran-7-...)
Affinity DataIC50: <4nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6218(AZD0530 analogue 34 | Chlorobenzodioxole deriv. 27...)
Affinity DataIC50:  5nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12253(AZD0530 analogue 31 | N-(5-chloro-2H-1,3-benzodiox...)
Affinity DataIC50:  5nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12259(AZD0530 analogue 37 | N-(5-chloro-2H-1,3-benzodiox...)
Affinity DataIC50:  5nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6218(AZD0530 analogue 34 | Chlorobenzodioxole deriv. 27...)
Affinity DataIC50:  5nMT: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12238(AZD0530 analogue 16 | N-(5-chloro-2H-1,3-benzodiox...)
Affinity DataIC50:  6nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12240(AZD0530 analogue 18 | N-(5-Chloro-1,3-benzodioxol-...)
Affinity DataIC50:  6nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12251(AZD0530 analogue 29 | N-(5-chloro-2H-1,3-benzodiox...)
Affinity DataIC50:  7nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12246(AZD0530 analogue 24 | N-(5-Chloro-1,3-benzodioxol-...)
Affinity DataIC50:  9.5nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6198(AZD0530 analogue 35 | M475271 | Methoxy Aniline 7 ...)
Affinity DataIC50:  10nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6220(4-[({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]-6...)
Affinity DataIC50:  10nMT: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6216(Benzodioxole deriv. 25 | N-(5-Chloro-1,3-benzodiox...)
Affinity DataIC50:  10nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12228(AZD0530 analogue 6 | N-(5-chloro-2H-1,3-benzodioxo...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6202(Benzofuran deriv. 11 | N-(6-Chloro-1-benzofuran-7-...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6198(AZD0530 analogue 35 | M475271 | Methoxy Aniline 7 ...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6196(Methoxy Aniline 5 | N-(2-Chloro-5-methoxyphenyl)-6...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6200(Benzofuran deriv. 9 | N-(5-Chloro-1-benzofuran-4-y...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6209(Benzodioxole deriv. 18 | N-(1,3-Benzodioxol-4-yl)-...)
Affinity DataIC50:  14nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12258(AZD0530 analogue 36 | N-(5-chloro-2H-1,3-benzodiox...)
Affinity DataIC50:  15nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6199(Benzofuran deriv. 8 | N-(1-Benzofuran-4-yl)-6-meth...)
Affinity DataIC50:  16nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12254(1-{4-[2-({4-[(5-fluoro-2H-1,3-benzodioxol-4-yl)ami...)
Affinity DataIC50:  20nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6208(Indole deriv. 17 | N-(3-Chloro-1H-indol-7-yl)-6-me...)
Affinity DataIC50:  20nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12229(AZD0530 analogue 7 | CHEMBL200217 | N-(2-Chloro-5-...)
Affinity DataIC50:  20nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12230(AZD0530 analogue 8 | N-(2-chloro-5-methoxyphenyl)-...)
Affinity DataIC50:  20nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6212(Benzodioxole deriv. 21 | N-(5-Fluoro-1,3-benzodiox...)
Affinity DataIC50:  28nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12232(AZD0530 analogue 10 | CHEMBL381206 | N-(2-chloro-5...)
Affinity DataIC50:  30nMAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12227(AZD0530 analogue 5 | N-(2-Chloro-5-methoxyphenyl)-...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6201(Benzofuran deriv. 10 | N-(1-Benzofuran-7-yl)-6-met...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6193(6-Methoxy-N-(3-methoxyphenyl)-7-(3-morpholin-4-ylp...)
Affinity DataIC50:  37nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12243(AZD0530 analogue 21 | N-(2-chloro-5-methoxyphenyl)...)
Affinity DataIC50:  40nMAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12232(AZD0530 analogue 10 | CHEMBL381206 | N-(2-chloro-5...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6206(6-Methoxy-N-(1-methyl-1H-indol-4-yl)-7-(3-morpholi...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12233(AZD0530 analogue 11 | N-(2H-1,3-benzodioxol-4-yl)-...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6217(Benzodioxole deriv. 26 | N-(5-Chloro-1,3-benzodiox...)
Affinity DataIC50:  50nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12231(AZD0530 analogue 9 | N-(2-chloro-5-methoxyphenyl)-...)
Affinity DataIC50:  50nMAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12239(AZD0530 analogue 17 | N-(2,3-Dihydro-1,4-benzodiox...)
Affinity DataIC50:  50nMAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12245(AZD0530 analogue 23 | N-(5-chloro-2H-1,3-benzodiox...)
Affinity DataIC50:  55nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12264(AZD0530 analogue 42 | N-(6-chloro-2,3-dihydro-1,4-...)
Affinity DataIC50:  65nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM12242(AZD0530 analogue 20 | N-(5-Chloro-1,3-benzodioxol-...)
Affinity DataIC50:  75nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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