TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 3.43E+3nMAssay Description:Mixed-type competitive inhibition of Xanthine oxidase (unknown origin) assessed as enzyme-inhibitor complex preincubated for 3 mins followed by xanth...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human HDAC after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human HDAC after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 386nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
Affinity DataIC50: 441nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 478nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Mus musculus (Mouse))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of mouse wild type PI3Kalpha expressed in Sf21 cells co-expressing N-terminal His-tagged human p85a using L-alpha-phosphatidylinositol sub...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of PI3Kdelta expressed in cells co-expressing N-terminal His-tagged human p85a using L-alpha-phosphatidylinositol substrate by TLC based p...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 591nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 608nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 808nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 838nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 927nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Inhibition of human wild type PI3Kbeta expressed in Sf21 cells co-expressing N-terminal His-tagged human p85a using L-alpha-phosphatidylinositol subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Mus musculus (Mouse))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of mouse wild type PI3Kalpha expressed in Sf21 cells co-expressing N-terminal His-tagged human p85a using L-alpha-phosphatidylinositol sub...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.51E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.98E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 6.04E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 6.23E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 6.36E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 8.26E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human HDAC after 30 minsMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 9.88E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAPKAPK2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of P38alpha (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant human NEK2 expressed in baculovirus infected sf21 cells using biotin labelled-STK-3 subs...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair