Affinity DataKi: 520nMAssay Description:Binding affinity to PPM1B (unknown origin) expressed in Escherichia coli BL21 assessed as inhibition constant using pNPP as substrate by absorbance b...More data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Inhibition of AXL (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant His-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) incubated for 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 359nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Protein kinase CMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of topoisomerase 1-mediated DNA relaxationMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of topoisomerase 1-mediated DNA relaxationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK-293 cells incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair