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Found 463 with Last Name = 'bamford' and Initial = 'sj'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254012(3-(4-Amino-3-fluorobenzyl)-7-(2-furyl)-3H-[1,2,3]t...)
Affinity DataKi:  0.700nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254353(3-(4-Amino-3-ethylbenzyl)-7-(2-furyl)-3H-[1,2,3]tr...)
Affinity DataKi:  1nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35836(pyrimidine-4-carboxamide, 118)
Affinity DataKi:  1nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254398(7-(2-Furyl)-3-(5-indolylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  1.10nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254013(3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]t...)
Affinity DataKi:  1.30nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254354(3-(4-Amino-3-isopropylbenzyl)-7-(2-furyl)-3H-[1,2,...)
Affinity DataKi:  1.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254009(3-(4-Aminobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  1.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254355(3-(4-Amino-3-hydroxybenzyl)-7-(2-furyl)-3H-[1,2,3]...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254356(7-(2-Furyl)-3-(4-(N-methylamino)benzyl)-3H-[1,2,3]...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50294501(2-amino-6-(furan-2-yl)-N-((6-(methoxymethyl)pyridi...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254004(7-(2-Furyl)-3-(3-methoxybenzyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  1.80nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254295(3-Benzyl-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyri...)
Affinity DataKi:  1.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253994(7-(2-Furyl)-3-(3-thienylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  1.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254300(3-(2,6-Difluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  1.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253995(3-(2-Aminobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  2nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254298(3-(2,4-Difluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  2nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35834(pyrimidine-4-carboxamide, 116)
Affinity DataKi:  2nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254000(3-(2-Fluorobenzyl)-7-(5-methyl-2-furyl)-3H-[1,2,3]...)
Affinity DataKi:  2.10nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50294507(2-amino-6-(furan-2-yl)-N-(2-methylbenzyl)pyrimidin...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254262(3-(2-Fluorobenzyl)-7-(4-methyl-2-thiazolyl)-3H-[1,...)
Affinity DataKi:  2.20nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254299(3-(2,5-Difluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  2.20nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253990(7-(2-Furyl)-3-(3-trifluoromethylbenzyl)-3H-[1,2,3]...)
Affinity DataKi:  2.20nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253987(3-(3-Chlorobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[...)
Affinity DataKi:  2.30nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254297(3-(2,3-Difluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  2.30nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253993(7-(2-Furyl)-3-(2-thienylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  2.30nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35833(pyrimidine-4-carboxamide, 115)
Affinity DataKi:  2.5nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254008(3-(3-Aminobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  2.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35829(pyrimidine-4-carboxamide, 111)
Affinity DataKi:  2.5nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50294505(2-amino-N-(2-chlorobenzyl)-6-(furan-2-yl)pyrimidin...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50294508(2-amino-6-(furan-2-yl)-N-(3-methylbenzyl)pyrimidin...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253999(3-(2-Fluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[...)
Affinity DataKi:  2.70nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35784(pyrimidine-4-carboxamide, 19 | pyrimidine-4-carbox...)
Affinity DataKi:  2.80nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35784(pyrimidine-4-carboxamide, 19 | pyrimidine-4-carbox...)
Affinity DataKi:  2.80nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253989(7-(2-Furyl)-3-(3-methylbenzyl)-3H-[1,2,3]triazolo[...)
Affinity DataKi:  3nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253988(7-(2-Furyl)-3-(2-methylbenzyl)-3H-[1,2,3]triazolo[...)
Affinity DataKi:  3nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35832(pyrimidine-4-carboxamide, 114)
Affinity DataKi:  3nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35843(pyrimidine-4-carboxamide, 28)
Affinity DataKi:  3nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35830(pyrimidine-4-carboxamide, 112)
Affinity DataKi:  3nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35837(pyrimidine-4-carboxamide, 119)
Affinity DataKi:  3.5nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50294510(2-amino-6-(furan-2-yl)-N-(2-methoxybenzyl)pyrimidi...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50294503(2-amino-N-(2-fluorobenzyl)-6-(furan-2-yl)pyrimidin...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254011(3-(4-Amino-2-fluorobenzyl)-7-(2-furyl)-3H-[1,2,3]t...)
Affinity DataKi:  3.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254301(7-(2-Furyl)-3-(3-nitrobenzyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  3.70nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50294506(2-amino-N-(3-chlorobenzyl)-6-(furan-2-yl)pyrimidin...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254005(3-(3-Cyanobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  3.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35786(pyrimidine-4-carboxamide, 27)
Affinity DataKi:  4nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254304(7-(2-Furyl)-3-(3-hydroxybenzyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  4nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254303(CHEMBL517429 | Methyl 3-(5-Amino-7-(2-furyl)-3H-[1...)
Affinity DataKi:  4.10nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35785(pyrimidine-4-carboxamide, 25)
Affinity DataKi:  4.30nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM35785(pyrimidine-4-carboxamide, 25)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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