TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 0.670nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 4.80nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 6.60nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 11.3nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 12.5nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 13.5nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 32.3nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 48.8nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of SGLT1 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 67.3nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of rat kidney NADPH-dependent aldose reductase assessed as DL-glyceraldehyde conversion to glycerol preincubated for 20 mins followed by N...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 108nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 123nMAssay Description:Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Council of Scientific & Industrial Research
US Patent
Council of Scientific & Industrial Research
US Patent
Affinity DataIC50: 129nMT: 2°CAssay Description:PDE3 inhibition assay was performed a BIOMOL GREEN Quantizyme Assay
System (catalogue No. BML-AK800-0001). The Platelets isolated from human
blood ...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 135nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 147nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 149nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 152nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 163nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 175nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 186nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 212nMAssay Description:Inhibition of rabbit lung ACE assessed as hydrolysis of hippuryl-histidyl-leucine to hippuric acid and histidyl-leucine after 30 minsMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 214nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of rat kidney NADPH-dependent aldose reductase assessed as DL-glyceraldehyde conversion to glycerol preincubated for 20 mins followed by N...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of SGLT1 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 227nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 253nMAssay Description:Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 253nMAssay Description:Inhibition of rabbit lung ACE assessed as hydrolysis of hippuryl-histidyl-leucine to hippuric acid and histidyl-leucine after 30 minsMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 257nMAssay Description:Inhibition of SGLT1 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 262nMAssay Description:Inhibition of rabbit lung ACE assessed as hydrolysis of hippuryl-histidyl-leucine to hippuric acid and histidyl-leucine after 30 minsMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 272nMAssay Description:Inhibition of rabbit lung ACE assessed as hydrolysis of hippuryl-histidyl-leucine to hippuric acid and histidyl-leucine after 30 minsMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 281nMAssay Description:Inhibition of rabbit lung ACE using hippuryl-histidyl-leucine as substrate assessed as release of hippuric acid incubated for 10 mins prior to substr...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 311nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 315nMAssay Description:Inhibition of SGLT1 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 315nMAssay Description:Inhibition of SGLT1 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 318nMAssay Description:Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 367nMAssay Description:Inhibition of SGLT2 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 376nMAssay Description:Inhibition of rabbit lung ACE assessed as hydrolysis of hippuryl-histidyl-leucine to hippuric acid and histidyl-leucine after 30 minsMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 392nMAssay Description:Inhibition of SGLT1 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 409nMAssay Description:Inhibition of rabbit lung ACE using hippuryl-histidyl-leucine as substrate assessed as release of hippuric acid incubated for 10 mins prior to substr...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 418nMAssay Description:Inhibition of rabbit lung ACE assessed as hydrolysis of hippuryl-histidyl-leucine to hippuric acid and histidyl-leucine after 30 minsMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 434nMAssay Description:Inhibition of SGLT1 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair